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1

The Exposome: Molecules to Populations

Niedzwiecki, Megan M., Walker, Douglas I., Vermeulen, Roel, Chadeau-Hyam, Marc, Jones, Dean P., Miller, Gary W.

Journal:

Annual Review of Pharmacology

Year:

2019

Language:

english

File:

PDF, 923 KB

english, 2019

2

Socioeconomic status and the 25 × 25 risk factors as determinants of premature mortality: a multicohort study and meta-analysis of 1·7 million men and women

Stringhini, Silvia, Carmeli, Cristian, Jokela, Markus, Avendaño, Mauricio, Muennig, Peter, Guida, Florence, Ricceri, Fulvio, d'Errico, Angelo, Barros, Henrique, Bochud, Murielle, Chadeau-Hyam, Marc, C

Journal:

Year:

2017

Language:

english

File:

PDF, 1.53 MB

english, 2017

3

Causal diagrams in systems epidemiology

Joffe, Michael, Gambhir, Manoj, Chadeau-Hyam, Marc, Vineis, Paolo

Journal:

Emerging Themes in Epidemiology

Year:

2012

Language:

english

File:

PDF, 675 KB

english, 2012

4

Blood transcriptional and microRNA responses to short-term exposure to disinfection by-products in a swimming pool

Espín-Pérez, Almudena, Font-Ribera, Laia, van Veldhoven, Karin, Krauskopf, Julian, Portengen, Lutzen, Chadeau-Hyam, Marc, Vermeulen, Roel, Grimalt, Joan O., Villanueva, Cristina M., Vineis, Paolo, Kog

Journal:

Environment International

Year:

2018

Language:

english

File:

PDF, 825 KB

english, 2018

5

Multi-cohort study identifies social determinants of systemic inflammation over the life course

Berger, Eloïse, Castagné, Raphaële, Chadeau-Hyam, Marc, Bochud, Murielle, d’Errico, Angelo, Gandini, Martina, Karimi, Maryam, Kivimäki, Mika, Krogh, Vittorio, Marmot, Michael, Panico, Salvatore, Preis

Journal:

Nature Communications

Year:

2019

Language:

english

File:

PDF, 684 KB

english, 2019

6

Socioeconomic status, non-communicable disease risk factors, and walking speed in older adults: multi-cohort population based study

Stringhini, Silvia, Carmeli, Cristian, Jokela, Markus, Avendaño, Mauricio, McCrory, Cathal, d’Errico, Angelo, Bochud, Murielle, Barros, Henrique, Costa, Giuseppe, Chadeau-Hyam, Marc, Delpierre, Cyrill

Journal:

Year:

2018

Language:

english

File:

PDF, 665 KB

english, 2018

7

327 A Compartmental hidden Markov model for the longitudinal analysis of the risk of smoking-Induced lung cancer

Chadeau-Hyam,, Vermeulen,, Vineis,

Journal:

Occupational and Environmental Medicine

Year:

2013

Language:

english

File:

PDF, 71 KB

english, 2013

8

The Impact of Air Pollution on Our Epigenome: How Far Is the Evidence? (A Systematic Review)

Alfano, Rossella, Herceg, Zdenko, Nawrot, Tim S., Chadeau-Hyam, Marc, Ghantous, Akram, Plusquin, Michelle

Journal:

Current Environmental Health Reports

Year:

2018

Language:

english

File:

PDF, 2.12 MB

english, 2018

9

R2GUESS : A Graphics Processing Unit-Based R Package for Bayesian Variable Selection Regression of Multivariate Responses

Liquet, Benoît, Bottolo, Leonardo, Campanella, Gianluca, Richardson, Sylvia, Chadeau-Hyam, Marc

Journal:

Journal Of Statistical Software

Year:

2016

Language:

english

File:

PDF, 2.78 MB

english, 2016

10

Exposome methods

J, Laine, B, Bodinier, M, Chadeau-Hyam, P, Vineis

Journal:

Environmental Epidemiology

Year:

2019

File:

PDF, 67 KB

2019

11

Determinants of accelerated metabolomic and epigenetic aging in a UK cohort

Robinson, Oliver, Chadeau Hyam, Marc, Karaman, Ibrahim, Climaco Pinto, Rui, Ala-Korpela, Mika, Handakas, Evangelos, Fiorito, Giovanni, Gao, He, Heard, Andy, Jarvelin, MarjoâRiitta, Lewis, Matthew, P

Journal:

Year:

2020

File:

PDF, 1.09 MB

2020

12

Special Report: The Biology of Inequalities in Health: The Lifepath Consortium

Vineis, Paolo, Avendano-Pabon, Mauricio, Barros, Henrique, Bartley, Mel, Carmeli, Cristian, Carra, Luca, Chadeau-Hyam, Marc, Costa, Giuseppe, Delpierre, Cyrille, D'Errico, Angelo, Fraga, Silvia, Giles

Journal:

Frontiers in Public Health

Year:

2020

File:

PDF, 2.84 MB

2020

13

An application of hidden Markov models to the French variant Creutzfeldt–Jakob disease epidemic

Marc Chadeau-Hyam, Paul S. Clarke, Chantal Guihenneuc-Jouyaux, Simon N. Cousens, Robert G. Will, Azra C. Ghani

Journal:

Journal of the Royal Statistical Society: Series C (Applied Statistics)

Year:

2010

Language:

english

File:

PDF, 950 KB

english, 2010

14

Metabolic Profiling and the Metabolome-Wide Association Study: Significance Level For Biomarker Identification

Chadeau-Hyam, Marc, Ebbels, Timothy M. D., Brown, Ian J., Chan, Queenie, Stamler, Jeremiah, Huang, Chiang Ching, Daviglus, Martha L., Ueshima, Hirotsugu, Zhao, Liancheng, Holmes, Elaine

Journal:

Journal of Proteome Research

Year:

2010

Language:

english

File:

PDF, 842 KB

english, 2010

15

Fregene: Simulation of realistic sequence-level data in populations and ascertained samples

Marc Chadeau-Hyam, Clive J Hoggart, Paul F O'Reilly, John C Whittaker, Maria De Iorio, David J Balding

Journal:

BMC Bioinformatics

Year:

2008

Language:

english

File:

PDF, 598 KB

english, 2008

16

Metabolome-Wide Association Study Identifies Multiple Biomarkers that Discriminate North and South Chinese Populations at Differing Risks of Cardiovascular Disease: INTERMAP Study

Yap, Ivan K. S., Brown, Ian J., Chan, Queenie, Wijeyesekera, Anisha, Garcia-Perez, Isabel, Bictash, Magda, Loo, Ruey Leng, Chadeau-Hyam, Marc, Ebbels, Timothy, Iorio, Maria De, Maibaum, Elaine, Zhao,

Journal:

Journal of Proteome Research

Year:

2010

Language:

english

File:

PDF, 1.46 MB

english, 2010

17

Prediagnostic transcriptomic markers of Chronic lymphocytic leukemia reveal perturbations 10 years before diagnosis

Chadeau-Hyam, M., Vermeulen, R. C. H., Hebels, D. G. A. J., Castagne, R., Campanella, G., Portengen, L., Kelly, R. S., Bergdahl, I. A., Melin, B., Hallmans, G., Palli, D., Krogh, V., Tumino, R., Sacer

Journal:

Annals of Oncology

Year:

2014

Language:

english

File:

PDF, 454 KB

english, 2014

18

Le nouveau variant de la maladie de Creutzfeldt-Jakob en France : estimation du nombre de cas attribuables à un séjour dans les îles britanniques entre 1980 et 1995

Chadeau-hyam, M., Alpérovitch, A.

Journal:

Revue d'Épidémiologie et de Santé Publique

Year:

2005

File:

PDF, 130 KB

2005

19

Western Pacific Regional ICM Conference

Chadeau-hyam, M., Alpérovitch, A.

Journal:

Australian College of Midwives Incorporated Journal

Year:

1988

Language:

english

File:

PDF, 85 KB

english, 1988

20

Deciphering the complex: Methodological overview of statistical models to derive OMICS-based biomarkers

Chadeau-Hyam, Marc, Campanella, Gianluca, Jombart, Thibaut, Bottolo, Leonardo, Portengen, Lutzen, Vineis, Paolo, Liquet, Benoit, Vermeulen, Roel C.H.

Journal:

Environmental and Molecular Mutagenesis

Year:

2013

Language:

english

File:

PDF, 250 KB

english, 2013

21

Biomarkers of ambient air pollution and lung cancer: a systematic review

Demetriou, C. A., Raaschou-Nielsen, O., Loft, S., Moller, P., Vermeulen, R., Palli, D., Chadeau-Hyam, M., Xun, W. W., Vineis, P.

Journal:

Occupational and Environmental Medicine

Year:

2012

Language:

english

File:

PDF, 771 KB

english, 2012

22

Advancing the application of omics-based biomarkers in environmental epidemiology

Vineis, Paolo, van Veldhoven, Karin, Chadeau-Hyam, Marc, Athersuch, Toby J.

Journal:

Environmental and Molecular Mutagenesis

Year:

2013

Language:

english

File:

PDF, 121 KB

english, 2013

23

Systems genetics identifies Sestrin 3 as a regulator of a proconvulsant gene network in human epileptic hippocampus

Johnson, Michael R., Behmoaras, Jacques, Bottolo, Leonardo, Krishnan, Michelle L., Pernhorst, Katharina, Santoscoy, Paola L. Meza, Rossetti, Tiziana, Speed, Doug, Srivastava, Prashant K., Chadeau-Hyam

Journal:

Nature Communications

Year:

2015

Language:

english

File:

PDF, 2.85 MB

english, 2015

24

Meeting-in-the-middle using metabolic profiling – a strategy for the identification of intermediate biomarkers in cohort studies

Chadeau-Hyam, Marc, Athersuch, Toby J., Keun, Hector C., De Iorio, Maria, Ebbels, Timothy M.D., Jenab, Mazda, Sacerdote, Carlotta, Bruce, Stephen J, Holmes, Elaine, Vineis, Paolo

Journal:

Year:

2011

Language:

english

File:

PDF, 736 KB

english, 2011

25

Dietary and Urinary Metabonomic Factors Possibly Accounting for Higher Blood Pressure of Black Compared With White Americans: Results of International Collaborative Study on Macro-/Micronutrients and Blood Pressure

Stamler, J., Brown, I. J., Yap, I. K. S., Chan, Q., Wijeyesekera, A., Garcia-Perez, I., Chadeau-Hyam, M., Ebbels, T. M. D., De Iorio, M., Posma, J., Daviglus, M. L., Carnethon, M., Holmes, E., Nichols

Journal:

Year:

2013

Language:

english

File:

PDF, 887 KB

english, 2013

26

Sequence-Level Population Simulations Over Large Genomic Regions

Hoggart, C. J., Chadeau-Hyam, M., Clark, T. G., Lampariello, R., Whittaker, J. C., De Iorio, M., Balding, D. J.

Journal:

Year:

2007

Language:

english

File:

PDF, 1.20 MB

english, 2007

27

The time machine: a simulation approach for stochastic trees

Jasra, A., De Iorio, M., Chadeau-Hyam, M.

Journal:

Proceedings Mathematical Physical & Engineering Sciences

Year:

2011

Language:

english

File:

PDF, 510 KB

english, 2011

28

Dynamics of the Risk of Smoking-Induced Lung Cancer

Chadeau-Hyam, Marc, Tubert-Bitter, Pascale, Guihenneuc-Jouyaux, Chantal, Campanella, Gianluca, Richardson, Sylvia, Vermeulen, Roel, De Iorio, Maria, Galea, Sandro, Vineis, Paolo

Journal:

Year:

2014

Language:

english

File:

PDF, 489 KB

english, 2014

29

Risk of variant Creutzfeldt-Jakob disease in France

Chadeau-Hyam, M.

Journal:

International Journal of Epidemiology

Year:

2004

Language:

english

File:

PDF, 167 KB

english, 2004

30

Inflammatory markers in relation to long-term air pollution

Mostafavi, Nahid, Vlaanderen, Jelle, Chadeau-Hyam, Marc, Beelen, Rob, Modig, Lars, Palli, Domenico, Bergdahl, Ingvar A., Vineis, Paolo, Hoek, Gerard, Kyrtopoulos, Soterios Α., Vermeulen, Roel

Journal:

Environment International

Year:

2015

Language:

english

File:

PDF, 366 KB

english, 2015

31

Estimation of the exposure of the French population to the BSE agent: comparison of the 1980–95 consumption of beef products containing mechanically recovered meat in France and the UK, by birth cohort and gender

Chadeau-Hyam, Marc, Tard, Alexandra, Bird, Sheila, Le Guennec, Solenn, Bemrah, Nawel, Volatier, Jean-Luc, Alpérovitch, Annick

Journal:

Statistical Methods in Medical Research

Year:

2003

Language:

english

File:

PDF, 223 KB

english, 2003

32

GUESS-ing Polygenic Associations with Multiple Phenotypes Using a GPU-Based Evolutionary Stochastic Search Algorithm

Bottolo, Leonardo, Chadeau-Hyam, Marc, Hastie, David I., Zeller, Tanja, Liquet, Benoit, Newcombe, Paul, Yengo, Loic, Wild, Philipp S., Schillert, Arne, Ziegler, Andreas, Nielsen, Sune F., Butterworth,

Journal:

Year:

2013

Language:

english

File:

PDF, 1.15 MB

english, 2013

33

ESS++: a C++ objected-oriented algorithm for Bayesian stochastic search model exploration

Bottolo, L., Chadeau-Hyam, M., Hastie, D. I., Langley, S. R., Petretto, E., Tiret, L., Tregouet, D., Richardson, S.

Journal:

Year:

2011

Language:

english

File:

PDF, 130 KB

english, 2011

34

A statistical framework to model the meeting-in-the-middle principle using metabolomic data: application to hepatocellular carcinoma in the EPIC study

Assi, Nada, Fages, Anne, Vineis, Paolo, Chadeau-Hyam, Marc, Stepien, Magdalena, Duarte-Salles, Talita, Byrnes, Graham, Boumaza, Houda, Knüppel, Sven, Kühn, Tilman, Palli, Domenico, Bamia, Christina, B

Journal:

Year:

2015

Language:

english

File:

PDF, 1.27 MB

english, 2015

35

Dynamic Aspects of Exposure History—Do They Matter?

Vermeulen, Roel, Chadeau-Hyam, Marc

Journal:

Year:

2012

Language:

english

File:

PDF, 321 KB

english, 2012

36

Integrating biomarkers into molecular epidemiological studies

Vineis, Paolo, Chadeau-Hyam, Marc

Journal:

Current Opinion in Oncology

Year:

2011

Language:

english

File:

PDF, 231 KB

english, 2011

37

The exposome in practice: design of the EXPOsOMICS project

Vineis, P., Chadeau-Hyam, M., Gmuender, H., Gulliver, J., Herceg, Z., Kleinjans, J., Kogevinas, M., Kyrtopoulos, S., Nieuwenhuijsen, M., Phillips, D., Probst-Hensch, N., Scalbert, A., Vermeulen, R., W

Journal:

International Journal of Hygiene and Environmental Health

Year:

2016

Language:

english

File:

PDF, 1.51 MB

english, 2016

38

The time machine: a simulation approach for stochastic trees

Ajay Jasra, Maria De Iorio and Marc Chadeau-Hyam

Journal:

Proceedings Mathematical Physical & Engineering Sciences

Year:

2011

Language:

english

File:

PDF, 1.68 MB

english, 2011

39

DNA methylation changes measured in pre-diagnostic peripheral blood samples are associated with smoking and lung cancer risk

Baglietto, Laura, Ponzi, Erica, Haycock, Philip, Hodge, Allison, Bianca Assumma, Manuela, Jung, Chol-Hee, Chung, Jessica, Fasanelli, Francesca, Guida, Florence, Campanella, Gianluca, Chadeau-Hyam, Mar

Journal:

International Journal of Cancer

Year:

2016

Language:

english

File:

PDF, 1.13 MB

english, 2016

40

Omics for prediction of environmental health effects: Blood leukocyte-based cross-omic profiling reliably predicts diseases associated with tobacco smoking

Georgiadis, Panagiotis, Hebels, Dennie G., Valavanis, Ioannis, Liampa, Irene, Bergdahl, Ingvar A., Johansson, Anders, Palli, Domenico, Chadeau-Hyam, Marc, Chatziioannou, Aristotelis, Jennen, Danyel G.

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 1.10 MB

english, 2016

41

From the exposome to mechanistic understanding of chemical-induced adverse effects

Escher, Beate I., Hackermüller, Jörg, Polte, Tobias, Scholz, Stefan, Aigner, Achim, Altenburger, Rolf, Böhme, Alexander, Bopp, Stephanie K., Brack, Werner, Busch, Wibke, Chadeau-Hyam, Marc, Covaci, Ad

Journal:

Environment International

Year:

2017

Language:

english

File:

PDF, 1.49 MB

english, 2017

42

Blood-based omic profiling supports female susceptibility to tobacco smoke-induced cardiovascular diseases

Chatziioannou, Aristotelis, Georgiadis, Panagiotis, Hebels, Dennie G., Liampa, Irene, Valavanis, Ioannis, Bergdahl, Ingvar A., Johansson, Anders, Palli, Domenico, Chadeau-Hyam, Marc, Siskos, Alexandro

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 810 KB

english, 2017

43

Associations Between Genome-wide Gene Expression and Ambient Nitrogen Oxides

Mostafavi, Nahid, Vlaanderen, Jelle, Portengen, Lutzen, Chadeau-Hyam, Marc, Modig, Lars, Palli, Domenico, Bergdahl, Ingvar A., Brunekreef, Bert, Vineis, Paolo, Hebels, Dennie G. A. J., Kleinjans, Jos

Journal:

Year:

2017

Language:

english

File:

PDF, 143 KB

english, 2017

44

Acute changes in serum immune markers due to swimming in a chlorinated pool

Vlaanderen, Jelle, van Veldhoven, Karin, Font-Ribera, Laia, Villanueva, Cristina M., Chadeau-Hyam, Marc, Portengen, Lützen, Grimalt, Joan O., Zwiener, Christian, Heederik, Dick, Zhang, Xiangru, Vineis

Journal:

Environment International

Year:

2017

Language:

english

File:

PDF, 603 KB

english, 2017

45

0380 Dynamics of Exposure and Disease Progression: The Use of Compartmental Models

Chadeau-Hyam, Marc

Journal:

Occupational and Environmental Medicine

Year:

2014

Language:

english

File:

PDF, 74 KB

english, 2014

46

Prediagnostic plasma concentrations of organochlorines and risk of B-cell non-Hodgkin lymphoma in envirogenomarkers: a nested case-control study

Kelly, Rachel S., Kiviranta, Hannu, Bergdahl, Ingvar A., Palli, Domenico, Johansson, Ann-Sofie, Botsivali, Maria, Vineis, Paolo, Vermeulen, Roel, Kyrtopoulos, Soterios A., Chadeau-Hyam, Marc

Journal:

Environmental Health

Year:

2017

Language:

english

File:

PDF, 433 KB

english, 2017

47

Refinement of a Methodology for Untargeted Detection of Serum Albumin Adducts in Human Populations

Preston, George W., Plusquin, Michelle, Sozeri, Osman, van Veldhoven, Karin, Bastian, Lilian, Nawrot, Tim S., Chadeau-Hyam, Marc, Phillips, David H.

Journal:

Chemical Research in Toxicology

Year:

2017

Language:

english

File:

PDF, 1.18 MB

english, 2017

48

0220 Identification of short-term, long-term and lifelong DNA methylation markers of exposure to tobacco smoke: evidence from EPIC and NOWAC studies

Guida, Florence, Campanella, Gianluca, Sandanger, Torkjel, Lund, Eiliv, Vermeulen, Roel, Vineis, Paolo, Chadeau-Hyam, Marc

Journal:

Occupational and Environmental Medicine

Year:

2014

Language:

english

File:

PDF, 77 KB

english, 2014

49

The human circulating miRNome reflects multiple organ disease risks in association with short-term exposure to traffic-related air pollution

Krauskopf, Julian, Caiment, Florian, van Veldhoven, Karin, Chadeau-Hyam, Marc, Sinharay, Rudy, Chung, Kian Fan, Cullinan, Paul, Collins, Peter, Barratt, Benjamin, Kelly, Frank J., Vermeulen, Roel, Vin

Journal:

Environment International

Year:

2018

Language:

english

File:

PDF, 864 KB

english, 2018

50

Allostatic load and subsequent all-cause mortality: which biological markers drive the relationship? Findings from a UK birth cohort

Castagné, Raphaële, Garès, Valérie, Karimi, Maryam, Chadeau-Hyam, Marc, Vineis, Paolo, Delpierre, Cyrille, Kelly-Irving, Michelle

Journal:

European Journal of Epidemiology

Year:

2018

Language:

english

File:

PDF, 2.05 MB

english, 2018

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